Clinical impact of tumor volume reduction in rectal cancer following preoperative chemoradiation
نویسندگان
چکیده
منابع مشابه
Preoperative Chemoradiation Therapy for Rectal Cancer.
The surgeon and the radiation therapist share the primary responsibility for the maintenance of local control in the management of carcinoma of the rectum. Usually, radiation therapy is used to control microscopic disease, while surgery is employed to control macroscopic disease. For ionizing radiation to be effective, targeted tissues must be well oxygenated. Likewise, the risk of local recurr...
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BACKGROUND Preoperative chemoradiation (CRT) is considered the standard of care in the management of stage II/III rectal cancer. The aim of this retrospective study was to assess the efficacy and safety of preoperative CRT in our patient cohort with locally advanced rectal adenocarcinoma. METHODS Forty patients with cT3-4N0-2M0 adenocarcinoma of the lower (n = 26) and mid/upper (n = 14) rectu...
متن کاملPreoperative chemoradiation with capecitabine in locally advanced rectal cancer.
BACKGROUND Preoperative radiation therapy in combination with 5-fluoracil (5-FU) improves local tumour control in locally advanced rectal cancer. The aim of our study was to evaluate the toxicity and efficacy of preoperative chemoradiation using the oral 5-FU prodrug capecitabine in locally advanced rectal cancer. METHODS Sixty patients with locally advanced rectal cancer were treated with pr...
متن کاملPrognostic Impact of Immunonutritional Status Changes During Preoperative Chemoradiation in Patients With Rectal Cancer
PURPOSE Previous studies have demonstrated the prognostic impact of the prognostic nutritional index (PNI), a proposed indicator of immunonutritional statuses of surgical patients, on patients with various gastrointestinal cancers. Although the prognostic impact of the PNI on patients with colorectal cancer has been well established, its value has not been studied in patients treated with preop...
متن کاملImpact of preoperative staging and chemoradiation versus postoperative chemoradiation on outcome in patients with rectal cancer: a decision analysis.
BACKGROUND Although radical resection and postoperative chemoradiation have been the standard therapy for patients with rectal cancer, preoperative staging by local imaging and chemoradiation are widely used. We used a decision analysis to compare the two strategies for rectal cancer management. METHODS We developed a decision model to compare survival outcomes after postoperative chemoradiat...
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ژورنال
عنوان ژورنال: Diagnostic and Interventional Imaging
سال: 2016
ISSN: 2211-5684
DOI: 10.1016/j.diii.2016.05.004